HPE ProLiant compatibility hub

Which HPE ProLiant servers support 26TB drives?

Verified spec guide ·

This compatibility hub covers HPE 26TB Business Critical LFF drives, P80577-B21 SAS and P80578-B21 SATA, only where current HPE documentation has been checked.

Server generation alone is not enough. The server must have the right LFF chassis, backplane, controller, firmware and option suffix for the exact drive.

Left
P80577-B21
Right
P80578-B21
Decision
Price and workload fit
Availability
Live rows below
Quick answer

DL380 Gen12 has the clearest current HPE documentation for both 26TB SAS and SATA options. DL360 Gen11 and ML350 Gen11 require LFF-specific configuration checks before ordering.

Compatibility rule
OEM procurement check

Verify the part number, carrier, firmware, sector format and server or storage-array qualification before ordering. A bare mechanism or third-party compatible listing can be useful, but it is an alternative unless it is sold as the qualified OEM kit or spare you need.

HPE 26TB ProLiant compatibility matrix

Only rows with verified HPE documentation are included. A physical 3.5-inch bay is not enough; the option must be qualified for the exact server, chassis and controller path.

ServerProLiant DL380 Gen12
GenerationGen12
26TB SASP80577-B21 listed
26TB SATAP80578-B21 listed
LFF requiredYes, LFF low-profile
Controller notesUse supported Gen12 Smart Array/HBA path and current firmware; do not generalize all SFF/EDSFF variants
Verified sourceHPE DL380 Gen12 QuickSpecs
ServerProLiant DL360 Gen11
GenerationGen11
26TB SASListed in LFF drive options
26TB SATAP80578-B21 listed
LFF requiredYes, 4LFF chassis
Controller notesController selection matters; internal MR and SR controllers cannot be selected together in HPE notes
Verified sourceHPE DL360 Gen11 QuickSpecs
ServerProLiant ML350 Gen11
GenerationGen11
26TB SASConditional on LFF SAS/SATA cage support
26TB SATAConditional on LFF SAS/SATA cage support
LFF requiredYes, 4LFF cages up to 12 LFF
Controller notesTri-mode/controller-mode cabling and SR controller choices affect supported drive paths
Verified sourceHPE ML350 Gen11 QuickSpecs

P80577-B21 26TB SAS vs P80578-B21 26TB SATA

The interface headline is only one line item. Qualification, carrier, controller and firmware path decide whether the drive is actually buyable for your system.

FeatureOption
P80577-B21 26TB SASP80577-B21
P80578-B21 26TB SATAP80578-B21
FeatureInterface
P80577-B21 26TB SAS12Gb/s SAS
P80578-B21 26TB SATA6Gb/s SATA
FeatureCapacity
P80577-B21 26TB SAS26TB
P80578-B21 26TB SATA26TB
FeatureForm factor
P80577-B21 26TB SAS3.5-inch LFF low-profile
P80578-B21 26TB SATA3.5-inch LFF low-profile
FeatureSector format
P80577-B21 26TB SAS512e
P80578-B21 26TB SATA512e
FeatureEncryption
P80577-B21 26TB SASISE
P80578-B21 26TB SATAISE
Current market status

No exact in-stock live row is currently matched for P80577-B21 / P80578-B21. Relevant live alternatives are shown for pricing context; verify qualification before treating any row as a substitute.

Exact rows plus compatible alternatives to verify

Live prices · updated every 4-5 hours · last checked 31 min ago · one side may be unavailable; alternatives are not exact OEM replacements

Best $/TB in this tier
1TB ST31000640SS CMR at $14.99/TB — $15 for 1TB
1TB ST31000640SS
CMR
1TB · 7200rpm · TB/yr · yr
$14.99/TB · $15Buy
4TB 695842-001
CMR
4TB · 7200rpm · TB/yr · yr
$15.00/TB · $60Buy
1TB 508011-001
CMR
1TB · 7200rpm · TB/yr · yr
$26.99/TB · $27Buy
24TB WUH722424ALE604
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$28.71/TB · $689Buy
24TB ST24000NM002H
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$29.17/TB · $700Buy
12TB MB012000GWWFE
CMR
12TB · 7200rpm · TB/yr · 5yr
$30.00/TB · $360Buy
4TB 846523-004
CMR
4TB · 7200rpm · TB/yr · yr
$30.00/TB · $120Buy
8TB 834031-B21
CMR
8TB · 7200rpm · TB/yr · yr
$32.75/TB · $262Buy
2TB AP072B321
CMR
2TB · 7200rpm · TB/yr · yr
$34.49/TB · $69Buy
12TB MB012000GWWFE
CMR
12TB · 7200rpm · TB/yr · 5yr
$34.50/TB · $414Buy
24TB ST24000DM001
CMR
24TB · 7200rpm · TB/yr · yr
$35.83/TB · $860Buy
26TB WD260KFGX
CMR
26TB · 7200rpm · TB/yr · yr
$43.25/TB · $1124Buy
24TB WD241KFGX
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$44.17/TB · $1060Buy
24TB ST24000NM000H
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$58.37/TB · $1401Buy

Workload rating is recorded per part number from the manufacturer's published data for that exact model where available, not blanketed across the line — two drives of the same capacity can differ because they are different generations. A dash means the figure is not stated for that listing. Recording technology comes from the manufacturer's published CMR/SMR list; a model absent from that list is shown as UNVERIFIED rather than guessed. Rows priced above 3× this line's in-stock median are flagged and excluded from the winner callout and from every median we compute.

Live acquisition math for exact comparison rows

This table is computed from live DatacenterDisk rows when an exact in-stock match exists. It is intentionally blank for unavailable models rather than filled with stale prices.

No exact in-stock row is available right now. Use the availability table for nearby live alternatives, then re-check the exact model before ordering.

SFF versus LFF

The HPE 26TB options here are LFF low-profile drives. SFF and EDSFF server builds do not become 3.5-inch capacity platforms with adapters, and a model name alone does not tell you which bay layout is installed.

Controller and firmware

HPE Smart Array or HBA support is part of the compatibility decision. The drive may need the current firmware path and an option suffix appropriate to the server family.

Mixed configurations

Avoid mixing capacity, sector format or interface inside a production drive group unless the HPE controller documentation explicitly supports the combination and the operational risk is acceptable.

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DL380 Gen12
26TB LFF guide
DL360 Gen11
4LFF guide
ML350 Gen11
12LFF tower guide
HPE storage hub
HPE drives and ProLiant parts
SAS HDDs
12Gb SAS enterprise drives
SATA HDDs
6Gb SATA capacity drives
SAS vs SATA
Interface tradeoffs
Server parts
Controllers, carriers and upgrades

Frequently asked questions

Which ProLiant page should I start with?

Start with the exact server page: DL380 Gen12, DL360 Gen11 or ML350 Gen11. Then confirm the drive option in HPE's current QuickSpecs.

Does every LFF ProLiant support 26TB?

No. LFF physical fit is only one requirement. HPE qualification, controller support and firmware decide the answer.

What if HPE documentation is unclear?

Treat the purchase as conditional and verify the exact system configuration or official option matrix before ordering.

Sources

Specification claims on this page were checked against the pages below on 1 September 2026. Where a widely-repeated figure did not survive that check, we report what the source says now and say so in the text rather than repeating the familiar number.

  1. Hewlett Packard Enterprise - HPE Server Enterprise and Midline Hard Drives QuickSpecs (HPE.com, 2026-09-01)
    Used for: P80577-B21 and P80578-B21 option identities; 26TB capacity; 12G SAS and 6G SATA variants; 7.2K LFF low-profile Business Critical class; 512e ISE status; 24TB P68583-B21 and P68585-B21 comparators; HPE drive qualification, digitally signed firmware and one-year Midline warranty treatment
  2. Hewlett Packard Enterprise - HPE ProLiant DL380 Gen12 QuickSpecs (HPE.com, 2026-09-01)
    Used for: DL380 Gen12 chassis and LFF/SFF storage configurations, including 8LFF and 12LFF chassis notes and inclusion of P80577-B21/P80578-B21 in supported storage options
  3. Hewlett Packard Enterprise - HPE ProLiant DL360 Gen11 QuickSpecs (HPE.com, 2026-09-01)
    Used for: DL360 Gen11 4LFF low-profile SAS/SATA chassis, supported LFF drive option list and Smart Array controller caveats
  4. Hewlett Packard Enterprise - HPE ProLiant ML350 Gen11 QuickSpecs (HPE.com, 2026-09-01)
    Used for: ML350 Gen11 4LFF SAS/SATA cage, up to 12 LFF hot-plug configuration and controller/cable notes for Gen11 storage cages
  5. DatacenterDisk - Live enterprise drive catalogue (DatacenterDisk.com, Live)
    Used for: current stock, seller condition, price per drive and price per terabyte values rendered in the live tables