DL380 Gen12 storage compatibility

HPE 26TB drives in ProLiant DL380 Gen12

Verified spec guide ·

The DL380 Gen12 is the strongest HPE 26TB fit in this batch because HPE's current QuickSpecs list both P80577-B21 SAS and P80578-B21 SATA among supported storage options.

Compatibility still depends on the exact chassis. A DL380 Gen12 SFF or EDSFF build is not the same purchase as a 12LFF storage build.

Model
P80577-B21
Capacity
26TB
Recording
Helium nearline CMR class; HPE lists the option as multi-vendor
Interface
12Gb/s SAS
Quick answer

DL380 Gen12 supports HPE 26TB Business Critical drives where the documented LFF chassis and controller path qualify them. A verified 12-front-LFF population is 12 x 26TB = 312TB raw before RAID or filesystem overhead.

Use 26TB in DL380 Gen12 when
OEM procurement check

Verify the part number, carrier, firmware, sector format and server or storage-array qualification before ordering. A bare mechanism or third-party compatible listing can be useful, but it is an alternative unless it is sold as the qualified OEM kit or spare you need.

DL380 Gen12 26TB deployment matrix

Only use the raw-capacity rows for configurations HPE documents with LFF drive bays.

Configuration12LFF front
26TB SASP80577-B21 listed
26TB SATAP80578-B21 listed
Raw capacity example12 x 26TB = 312TB raw
CaveatVerify exact chassis, backplane, controller and firmware
Configuration8LFF front plus expansion positions
26TB SASLFF path documented
26TB SATALFF path documented
Raw capacity exampleDo not assume all 20 possible LFF positions support 26TB
CaveatHPE's maximum-storage summary may lag option table capacity
ConfigurationSFF / EDSFF chassis
26TB SASNot an LFF HDD target
26TB SATANot an LFF HDD target
Raw capacity exampleNo 3.5-inch 26TB HDD bay
CaveatChoose the correct chassis at purchase
Current market status

No exact in-stock live row is currently matched for P80577-B21. Relevant live alternatives are shown for pricing context; verify qualification before treating any row as a substitute.

Compatible alternatives to verify, ranked by current $/TB

Live prices · updated every 4-5 hours · last checked 33 min ago · not exact OEM replacements; verify qualification, carrier, firmware and interface before ordering

Best $/TB in this tier
1TB ST31000640SS CMR at $14.99/TB — $15 for 1TB
1TB ST31000640SS
CMR
1TB · 7200rpm · TB/yr · yr
$14.99/TB · $15Buy
4TB 695842-001
CMR
4TB · 7200rpm · TB/yr · yr
$15.00/TB · $60Buy
1TB 508011-001
CMR
1TB · 7200rpm · TB/yr · yr
$26.99/TB · $27Buy
24TB WUH722424ALE604
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$28.71/TB · $689Buy
24TB ST24000NM002H
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$29.17/TB · $700Buy
12TB MB012000GWWFE
CMR
12TB · 7200rpm · TB/yr · 5yr
$30.00/TB · $360Buy
4TB 846523-004
CMR
4TB · 7200rpm · TB/yr · yr
$30.00/TB · $120Buy
8TB 834031-B21
CMR
8TB · 7200rpm · TB/yr · yr
$32.75/TB · $262Buy
2TB AP072B321
CMR
2TB · 7200rpm · TB/yr · yr
$34.49/TB · $69Buy
12TB MB012000GWWFE
CMR
12TB · 7200rpm · TB/yr · 5yr
$34.50/TB · $414Buy
24TB ST24000DM001
CMR
24TB · 7200rpm · TB/yr · yr
$35.83/TB · $860Buy
26TB WD260KFGX
CMR
26TB · 7200rpm · TB/yr · yr
$43.25/TB · $1124Buy
24TB WD241KFGX
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$44.17/TB · $1060Buy
24TB ST24000NM000H
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$58.37/TB · $1401Buy

Workload rating is recorded per part number from the manufacturer's published data for that exact model where available, not blanketed across the line — two drives of the same capacity can differ because they are different generations. A dash means the figure is not stated for that listing. Recording technology comes from the manufacturer's published CMR/SMR list; a model absent from that list is shown as UNVERIFIED rather than guessed. Rows priced above 3× this line's in-stock median are flagged and excluded from the winner callout and from every median we compute.

Live acquisition math for exact matches

This table is computed from live DatacenterDisk rows when an exact in-stock match exists. It is intentionally blank for unavailable models rather than filled with stale prices.

No exact in-stock row is available right now. Use the availability table for nearby live alternatives, then re-check the exact model before ordering.

P80577-B21 26TB SAS: procurement checks

Use this table before accepting a quote, especially when new, open-box, refurbished and bare-drive listings appear side by side.

CheckExact option
Why it mattersP80577-B21 must appear on the quote or listing when you need the exact OEM option.
CheckCarrier
Why it mattersHPE low-profile Smart Carrier option kit
CheckFirmware path
Why it mattersOEM-qualified firmware can decide update eligibility, health reporting and support handling.
CheckSector format
Why it matters512e must match the controller, array and existing drive group.
CheckCondition
Why it mattersNew, open-box, refurbished and used units should be compared as different offers, not as the same price point.
CheckSupport
Why it matters1-year limited warranty for HPE Midline hard drives

26TB raw capacity examples

Raw decimal capacity is shown before filesystem formatting, RAID, hot spares, snapshots or vendor overhead.

Drive count4 drives
Raw capacity104TB raw
Single-parity example78TB before formatting
Dual-parity example52TB before formatting
Drive count8 drives
Raw capacity208TB raw
Single-parity example182TB before formatting
Dual-parity example156TB before formatting
Drive count12 drives
Raw capacity312TB raw
Single-parity example286TB before formatting
Dual-parity example260TB before formatting

SAS or SATA in DL380 Gen12

Use P80577-B21 when SAS drive architecture or a SAS-standardized fleet is required. Use P80578-B21 when a qualified SATA path meets the workload and acquisition cost matters more than dual-port capability.

Raw capacity is not usable capacity

Twelve 26TB drives equal 312TB raw. After RAID, filesystem formatting, hot spares and reserved space, usable capacity is lower. Do not present 312TB as usable capacity in a purchase justification.

Configuration traps

HPE documents multiple DL380 Gen12 storage layouts. The 8LFF chassis cannot simply be assumed to become a 12-front-LFF chassis later, and SFF/EDSFF variants do not become 3.5-inch capacity platforms with adapters.

Share:WhatsAppFacebookPost on X
HPE compatibility hub
26TB support matrix
P80577-B21
26TB SAS option
P80578-B21
26TB SATA option
HPE storage hub
HPE drives and ProLiant parts
SAS HDDs
12Gb SAS enterprise drives
SATA HDDs
6Gb SATA capacity drives
SAS vs SATA
Interface tradeoffs
Server parts
Controllers, carriers and upgrades

Frequently asked questions

Does DL380 Gen12 support P80577-B21?

HPE's current DL380 Gen12 QuickSpecs list the P80577-B21 26TB SAS option. Confirm the exact LFF chassis and controller configuration before ordering.

Does DL380 Gen12 support P80578-B21?

HPE's current DL380 Gen12 QuickSpecs list the P80578-B21 26TB SATA option. Confirm the exact LFF chassis and controller configuration before ordering.

Is 12 x 26TB equal to 312TB usable?

No. It is 312TB raw decimal capacity before RAID, formatting, hot spares and filesystem overhead.

Sources

Specification claims on this page were checked against the pages below on 1 September 2026. Where a widely-repeated figure did not survive that check, we report what the source says now and say so in the text rather than repeating the familiar number.

  1. Hewlett Packard Enterprise - HPE ProLiant DL380 Gen12 QuickSpecs (HPE.com, 2026-09-01)
    Used for: DL380 Gen12 chassis and LFF/SFF storage configurations, including 8LFF and 12LFF chassis notes and inclusion of P80577-B21/P80578-B21 in supported storage options
  2. Hewlett Packard Enterprise - HPE Server Enterprise and Midline Hard Drives QuickSpecs (HPE.com, 2026-09-01)
    Used for: P80577-B21 and P80578-B21 option identities; 26TB capacity; 12G SAS and 6G SATA variants; 7.2K LFF low-profile Business Critical class; 512e ISE status; 24TB P68583-B21 and P68585-B21 comparators; HPE drive qualification, digitally signed firmware and one-year Midline warranty treatment
  3. Hewlett Packard Enterprise - HPE P80577-B21 product listing (HPE Buy, 2026-09-01)
    Used for: current HPE product name and SKU for the 26TB SAS Business Critical LFF low-profile 512e ISE option
  4. Hewlett Packard Enterprise - HPE P80578-B21 product listing (HPE Buy, 2026-09-01)
    Used for: current HPE product name and SKU for the 26TB SATA Business Critical LFF low-profile 512e ISE option
  5. DatacenterDisk - Live enterprise drive catalogue (DatacenterDisk.com, Live)
    Used for: current stock, seller condition, price per drive and price per terabyte values rendered in the live tables