ML350 Gen11 26TB storage

HPE 26TB drives in ProLiant ML350 Gen11

Verified spec guide ·

The ML350 Gen11 is a natural 26TB candidate for local business storage, backup, virtualization and archive use because HPE documents 4LFF SAS/SATA cages up to a 12LFF hot-plug drive model.

The important word is configuration. The drive cages, cabling and storage controller path must match the intended SAS or SATA option.

Model
P80578-B21
Capacity
26TB
Recording
Helium nearline CMR class; HPE lists the option as multi-vendor
Interface
6Gb/s SATA
Quick answer

ML350 Gen11 can be a 12LFF 26TB capacity platform only when the documented LFF SAS/SATA cages and controller path support the exact HPE option. Twelve 26TB drives are 312TB raw before RAID and filesystem overhead.

Use ML350 Gen11 for 26TB when
OEM procurement check

Verify the part number, carrier, firmware, sector format and server or storage-array qualification before ordering. A bare mechanism or third-party compatible listing can be useful, but it is an alternative unless it is sold as the qualified OEM kit or spare you need.

ML350 Gen11 26TB configuration checks

HPE documents the bay hardware; the purchase still needs controller and firmware verification.

ItemDrive cage
Verified detail4LFF SAS/SATA Basic cage supports up to 12 LFF as 4+4+4
Procurement impactNeeded for 3.5-inch 26TB drives
ItemHot-plug model
Verified detail12 LFF hot-plug drive model uses three 4LFF SAS/SATA cages
Procurement impact312TB raw with 12 x 26TB if qualified
ItemSAS option
Verified detailUse HPE 26TB SAS only where listed and controller-qualified
Procurement impactChoose for SAS-standardized environments
ItemSATA option
Verified detailUse HPE 26TB SATA only where listed and controller-qualified
Procurement impactOften enough for backup/archive capacity
ItemController/cabling
Verified detailHPE documents controller-mode and direct-attach caveats for cages
Procurement impactSettle this before purchase
Current market status

No exact in-stock live row is currently matched for P80578-B21. Relevant live alternatives are shown for pricing context; verify qualification before treating any row as a substitute.

Compatible alternatives to verify, ranked by current $/TB

Live prices · updated every 4-5 hours · last checked 32 min ago · not exact OEM replacements; verify qualification, carrier, firmware and interface before ordering

Best $/TB in this tier
1TB ST31000640SS CMR at $14.99/TB — $15 for 1TB
1TB ST31000640SS
CMR
1TB · 7200rpm · TB/yr · yr
$14.99/TB · $15Buy
4TB 695842-001
CMR
4TB · 7200rpm · TB/yr · yr
$15.00/TB · $60Buy
1TB 508011-001
CMR
1TB · 7200rpm · TB/yr · yr
$26.99/TB · $27Buy
24TB WUH722424ALE604
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$28.71/TB · $689Buy
24TB ST24000NM002H
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$29.17/TB · $700Buy
12TB MB012000GWWFE
CMR
12TB · 7200rpm · TB/yr · 5yr
$30.00/TB · $360Buy
4TB 846523-004
CMR
4TB · 7200rpm · TB/yr · yr
$30.00/TB · $120Buy
8TB 834031-B21
CMR
8TB · 7200rpm · TB/yr · yr
$32.75/TB · $262Buy
2TB AP072B321
CMR
2TB · 7200rpm · TB/yr · yr
$34.49/TB · $69Buy
12TB MB012000GWWFE
CMR
12TB · 7200rpm · TB/yr · 5yr
$34.50/TB · $414Buy
24TB ST24000DM001
CMR
24TB · 7200rpm · TB/yr · yr
$35.83/TB · $860Buy
26TB WD260KFGX
CMR
26TB · 7200rpm · TB/yr · yr
$43.25/TB · $1124Buy
24TB WD241KFGX
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$44.17/TB · $1060Buy
24TB ST24000NM000H
CMR
24TB · 7200rpm · 550TB/yr · 5yr
$58.37/TB · $1401Buy

Workload rating is recorded per part number from the manufacturer's published data for that exact model where available, not blanketed across the line — two drives of the same capacity can differ because they are different generations. A dash means the figure is not stated for that listing. Recording technology comes from the manufacturer's published CMR/SMR list; a model absent from that list is shown as UNVERIFIED rather than guessed. Rows priced above 3× this line's in-stock median are flagged and excluded from the winner callout and from every median we compute.

Live acquisition math for exact matches

This table is computed from live DatacenterDisk rows when an exact in-stock match exists. It is intentionally blank for unavailable models rather than filled with stale prices.

No exact in-stock row is available right now. Use the availability table for nearby live alternatives, then re-check the exact model before ordering.

26TB raw capacity examples

Raw decimal capacity is shown before filesystem formatting, RAID, hot spares, snapshots or vendor overhead.

Drive count4 drives
Raw capacity104TB raw
Single-parity example78TB before formatting
Dual-parity example52TB before formatting
Drive count8 drives
Raw capacity208TB raw
Single-parity example182TB before formatting
Dual-parity example156TB before formatting
Drive count12 drives
Raw capacity312TB raw
Single-parity example286TB before formatting
Dual-parity example260TB before formatting

Tower storage use cases

A 12LFF ML350 Gen11 can serve local backup, branch-office file storage, media archive, virtualization datastore staging and AI dataset holding areas. Those are capacity-first workloads where price, spares and rebuild policy matter as much as interface.

Do not generalize from bay count

A 12LFF raw-capacity calculation is valid only for a documented LFF build. It is not a promise about every ML350 Gen11 listing, and it is not a substitute for checking the Smart Array/HBA configuration.

Spares and condition

For branch or small-business deployments, buy at least one matching spare if downtime matters. New OEM kits, open-box spares and refurbished pulls can all appear in the market, but they should not be priced as equivalent offers.

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HPE compatibility hub
26TB support matrix
26TB vs 24TB
Capacity economics
HPE storage hub
HPE drives and ProLiant parts
SAS HDDs
12Gb SAS enterprise drives
SATA HDDs
6Gb SATA capacity drives
SAS vs SATA
Interface tradeoffs
Server parts
Controllers, carriers and upgrades

Frequently asked questions

How much raw capacity is 12 x 26TB?

Twelve 26TB drives provide 312TB raw decimal capacity before RAID, formatting and hot-spare overhead.

Is the ML350 Gen11 better with SAS or SATA?

It depends on the controller and workload. SATA can be sufficient for backup/archive. SAS is justified when the storage design or support policy requires it.

Can I buy bare 26TB drives for an ML350 Gen11?

Only as clearly understood alternatives. For HPE support and qualification, match the HPE option identity, carrier and firmware path.

Sources

Specification claims on this page were checked against the pages below on 1 September 2026. Where a widely-repeated figure did not survive that check, we report what the source says now and say so in the text rather than repeating the familiar number.

  1. Hewlett Packard Enterprise - HPE ProLiant ML350 Gen11 QuickSpecs (HPE.com, 2026-09-01)
    Used for: ML350 Gen11 4LFF SAS/SATA cage, up to 12 LFF hot-plug configuration and controller/cable notes for Gen11 storage cages
  2. Hewlett Packard Enterprise - HPE Server Enterprise and Midline Hard Drives QuickSpecs (HPE.com, 2026-09-01)
    Used for: P80577-B21 and P80578-B21 option identities; 26TB capacity; 12G SAS and 6G SATA variants; 7.2K LFF low-profile Business Critical class; 512e ISE status; 24TB P68583-B21 and P68585-B21 comparators; HPE drive qualification, digitally signed firmware and one-year Midline warranty treatment
  3. DatacenterDisk - Live enterprise drive catalogue (DatacenterDisk.com, Live)
    Used for: current stock, seller condition, price per drive and price per terabyte values rendered in the live tables